North Queensland Toyota Cowboys Head Coach Todd Payten has made a host of changes to his side to face Cronulla on the Sunshine Coast on Saturday afternoon.
Connelly Lemuelu, Ben Hampton, Shane Wright and Ben Condon have all been called up for their first NRL games of the 2021 season.
Lemuelu replaces Esan Marsters in the centres, with Murray Taulagi remaining on the wing after an impressive season debut in Round 3.
>>> Payten on team changes, & injuries
Ben Hampton is set to start his first game at halfback since 2015, partnering Scott Drinkwater with co-captain Michael Morgan still unavailable due to a shoulder injury, while Valentine Holmes retains the fullback spot.
Shane Wright and Ben Condon form a brand-new second row combination, with Mitch Dunn sidelined through a foot injury and Coen Hess reverting to the bench.
Reuben Cotter is also sidelined with a concussion, which sees Josh McGuire start at lock for the first time in 2021.
Hess is joined on the interchange by dummy-half Jake Granville and forwards Corey Jensen and Lachlan Burr.
Peter Hola, Marsters, Griffin Neame and Jake Clifford make up the reserves.
Saturday’s game starts at 4.30pm.
Cowboys team to play Sharks:
7. Ben Hampton
8. Francis Molo
9. Reece Robson
10. Jordan McLean (C)
11. Shane Wright
12. Ben Condon
13. Josh McGuire
14. Jake Granville
15. Coen Hess
16. Corey Jensen
17. Lachlan Burr
18. Peter Hola
19. Esan Marsters
20. Griffin Neame
21. Jake Clifford