North Queensland Toyota Cowboys centre Justin O'Neill will make his debut for Australia against Scotland in Hull on Friday (6am AEDT, Saturday 29 October).
O'Neill (Kangaroo No.813) is one of five debutants named by Kangaroos coach Mal Meninga for the opening Four Nations match at Hull's KC Lightstream Stadium.
Fullback Matt Moylan (812), five-eighth James Maloney (811), lock Jake Trbojevic (814) and interchange player Jake Friend (815) will also play in the green and gold jersey for the first time.
Cooper Cronk will play his 30th Test match for Australia against the Bravehearts, while O'Neill's club teammate Michael Morgan has been named on the bench.
"I always planned to ensure the entire 24-man squad has played across the Perth Test and the Four Nations match against Scotland and that will set us up nicely for the rest of the tournament," Kangaroos coach Mal Meninga said.
"I do have an idea of what my best possible squad would be but all players know they can break into the top team with a strong performance."
The match will be broadcast live on Channel 9.
Kangaroos squad to play Scotland:
1. Matt Moylan
2. Josh Mansour
3. Justin O'Neill
4. Josh Dugan
5. Blake Ferguson
6. James Maloney
7. Cooper Cronk
8. Aaron Woods
9. Cameron Smith (c)
10. David Klemmer
11. Sam Thaiday
12. Tyson Frizell
13. Jake Trbojevic
Interchange:
14. Jake Friend
15. Shannon Boyd
16. Trent Merrin
17. Michael Morgan
18. Valentine Holmes
19. Boyd Cordner
