North Queensland Toyota Cowboys fullback Te Maire Martin has been ruled out of tonight's sold-out clash with the Eels, which is Johnathan Thurston's last game at 1300SMILES Stadium, with an ankle injury.
Martin is replaced by Ben Hampton, who is set to start his first game at fullback since Round 5.
Ethan Lowe takes Hampton's place on the interchange and is joined by forwards John Asiata, Francis Molo and Scott Bolton.
Co-captain Matt Scott returns after being rested against Cronulla last week and celebrates his landmark 250th appearance for the Cowboys.
Scott becomes just the third player and first forward to reach the milestone, joining Thurston and club legend Matthew Bowen.
Star lock Jason Taumalolo also returns after missing the Cronulla clash through suspension, while hooker Jake Granville celebrates his 100th appearance for the club.
Match: Cowboys v Eels
Round 24 -
Fullback for Cowboys is number 14 Ben HamptonFullback for Eels is number 1 Corey Norman
Winger for Cowboys is number 2 Kyle FeldtWinger for Eels is number 2 Jarryd Hayne
Centre for Cowboys is number 3 Justin O'NeillCentre for Eels is number 3 Michael Jennings
Centre for Cowboys is number 4 Kane LinnettCentre for Eels is number 4 Clinton Gutherson
Winger for Cowboys is number 5 Gideon Gela-MosbyWinger for Eels is number 5 George Jennings
Five-Eighth for Cowboys is number 6 Jake CliffordFive-Eighth for Eels is number 6 Jaeman Salmon
Halfback for Cowboys is number 7 Johnathan ThurstonHalfback for Eels is number 7 Mitchell Moses
Prop for Cowboys is number 8 Matthew ScottProp for Eels is number 8 Kane Evans
Hooker for Cowboys is number 9 Jake GranvilleHooker for Eels is number 14 Cameron King
Prop for Cowboys is number 10 Jordan McLeanProp for Eels is number 10 Siosaia Vave
2nd Row for Cowboys is number 11 Gavin Cooper2nd Row for Eels is number 11 Marata Niukore
2nd Row for Cowboys is number 12 Coen Hess2nd Row for Eels is number 12 Tepai Moeroa
Lock for Cowboys is number 13 Jason TaumaloloLock for Eels is number 13 Peni Terepo
Interchange for Cowboys is number 15 John AsiataInterchange for Eels is number 9 Reed Mahoney
Interchange for Cowboys is number 16 Francis MoloInterchange for Eels is number 15 Tim Mannah
Interchange for Cowboys is number 17 Scott BoltonInterchange for Eels is number 16 David Gower
Interchange for Cowboys is number 18 Ethan LoweInterchange for Eels is number 17 Brad Takairangi
- Referee: Grant Atkins
- Referee: Phil Henderson
- Touch Judge: Tim Roby
- Senior Review Official: Jared Maxwell